The article covers non-IgE mediated disorders caused by food. It states that 40% of milk protein allergy in young children and infants is associated with Non-IgE. The author aims to review and provide updates on diagnosis of FPIAP (food protein-induced enterocolitis syndrome) and FPIAP (food protein-induced allergic proctocolitis) (Nowak-Wegrzyn). She reviews the manifestation of FPIES and points out the fact that it is mostly misdiagnosed as viral gastrointestinal illness and such delays could lead to food allergies. The author also uses other peer-reviewed articles which are indexed in PubMed. She also presents ondansetron as a solution in the introduction, hence bringing out a clear review that draws attention.
The article reveals that both FPIP and FPIES are diseases common in infants even though in some cases FPIES might manifest in adults. Both are associated with soy and CM as the offending foods that cause allergies. However, there is a difference between the two such that FPIP is common in breast feeding infants while FPIES is common in weaning infants (Nowak-Wegrzyn). If not discovered in their early stages, these diseases could be life threatening. The clinical features, epidemiology, history, testing treatment, management and prevention of both diseases are well covered even though children are always misdiagnosed more often than not.
The article clearly covers all clinical aspects of both diseases. The statistical data and evidence produced relates with the sources cited and the author brings out a good argument. However, I feel that she would have used other forms of data representation including graphs and pie charts. Also, the author should have introduced examples maybe from hospital data to help him pass the information. Otherwise, the author did a commendable job.
Nowak-Wegrzyn, Anna. “Food protein-induced enterocolitis syndrome and allergic proctocolitis”. Allergy and Asthma Proceedings, May-June 2015. Retrieved from; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405595/