Sample Nursing Paper on Human Subjects in Clinical Trials: Ethical Considerations and Concerns

Human Subjects in Clinical Trials: Ethical Considerations and Concerns

Performing a medical examination is a time and resource-intensive course. Critically, participant identification and maintenance are vital to lowering the cost and amount of time spent on clinical research. Conducting quality research plays a significant role in assessing the clinical and cost-effectiveness of healthcare systems and processes, while subject recruitment of adequate participants is a pillar for an efficient research process to test hypotheses with awash with confidence and non-discriminatorily. Various guidelines, such as the Good Clinical Practice (GCP) have been proposed to guarantee that medical research is steered scientifically and ethically. These regulations seek to protect the integrity, rights, and confidentiality of participant human subjects (W & Al-Sayed, 2018). With a history of horrific and unethical research, for instance, the German clinician’s trials at Nazi war cantonment during World War II, scientific research units have championed compliance to the ethical principles approved globally. In this regard, numerous committees and organizations have adopted different stipulations and documents that advocate for compliance with ethical principles, evidence-based research, benefits to outweigh risks, and a concise description of the appropriate protocol. Besides, obtaining informed consent from subjects or their guardians and affirming confidentiality are vital components of scientific human subject research. Moreover, proper and accurate data documentation is vital for the credibility of a study. The accessibility and availability of research findings are vital to determining the suitability and eligibility of research. Adhering to the GCP stipulations is vital for actualizing scientifically and ethically apt research (World Health Organization, 2020). Nonetheless, there is a need for further research to model the existing guidelines to enhance the recruitment process and protection of human subjects in clinical trials.

 

 

References

W, A., & Al-Sayed, M. (2018). Human subjects in clinical trials: Ethical considerations and concerns. Journal of Translational Science4(6). doi:10.15761/jts.1000239

World Health Organization. (2020). Ethical standards and procedures for research with human beings. Retrieved from https://www.who.int/teams/health-ethics-governance/governance/research