Sample Medicine Paper on High Peep Therapy with ARDS Patient

Abstract: High Peep Therapy with ARDS Patient

Background: Acute Respiratory Distress Syndrome (ARDS) is an ailment that affects the lungs and causes severe inflammation. PEEP or the positive end-expiratory pressure is among the treatments that have been identified to cure or stabilize the conditions of ARDS patients. PEEP can be applied in either high or lower volumes and the main question is which volumes are most efficient in stabilizing the lung inflammation. Studies examine the efficacy between high PEEP therapies of 20 cmH2O and above versus lower PEEP that is obviously lower than the indicated volume. Therefore, the purpose of this study was to identify which levels are the most appropriate in treating ARDS between high and low PEEP levels. Methods: relying on a study carried out by Matthias, B., Meade, M. & Alain, M. et al. (2010). “Higher vs. Lower Positive End-Expiratory Pressure in Patients with Acute Lung Injury and Acute Respiratory Distress Syndrome” it was easier to garner information. This study involved analyzing data from two medical websites, MEDLINE and EMBASE, that contained information for over 2000 patients diagnosed with ARDS. Other studies looked into included Raymondos, K., Ahrens, J., &Molitoris, U. (2015) who observed the case of a 75 old male patient who underwent through both high and low PEEP. Results. Among all the studies incorporated in this research show a tendency of high PEEP producing more positive results as compared to the low PEEP. For instance, Mathias et al found out that out of the 1136 patients treated under higher PEEP, 374 died as opposed to 409 hospital deaths in 1163 patients under lower PEEP. Conclusion.Mechanical ventilation with plateau pressure of 20 cm to 35 cm H2O which is high positive end-expiratory pressure (PEEP) is recommended and it seems that high initial PEEP values appeared to be beneficial.