Sample Medical Science Essay Paper on Cervical Spinal Cord Injury Treatment

Introduction

Numerous techniques have been diagnosed to cure animal spinal cord injury (SCI), but there has been limited success in efficiency of the drugs. Most of the SCI usually occurs at the cervical level, hence, leading to the infirmity of both the upper and lower ends. As such, the life of an individual is reduced which eventually leads to higher costs incurred during treatment of the disease (Iwasaki, Motoyuki, et al. 2617). Moreover, SCI can cause damage and disappearance of neural tissues and eventually leads to the creation of cystic cavities that prevents emerging axons from moving across the injured region. Unreceptive microenvironment considerably affects the conservation and growth of neural tissues (Iwasaki, Motoyuki, et al. 2617) negatively. Therefore, the research discusses the perspective, proposed techniques, and application of the research “Synergetic effects of self-assembling peptide and neural stem/progenitor cells to promote tissue repair and forelimb functional recovery in cervical spinal cord injury.”

Perspective of the Research

Various research has been conducted which has indicated success in restoration of outside cellular matrix to offer a useful scaffold for renewal of cells and axons to facilitate therapeutic effectiveness (Iwasaki, Motoyuki, et al. 2617). There has been development of self-assembling peptides (SAP) that enhance the creation of 3D arrangement of fibers in a biological environment without augmenting an immune reaction. Notably, the injection of K2 (QL) 6K2 (QL6) within 24 hours to the specimen proved vital in protecting histologic tissues by weakening the degree of swelling and astrogliosis of the limbs. Conversantly, this has helped in lowering post-traumatic apoptosis of the neural cells, hence, encouraging axonal growth of the thoracic affected rats (Iwasaki, Motoyuki, et al. 2618). In essence, the research employs the technique in transplanting neural stem cells to acquire the benefits and incorporate the system in a delayed SAP-based therapy. Hence, the investigation emphases on discovering an appropriate system of treating SCI. 

Proposed Techniques  

The study develops a rat-based model in which seventy-seven adult Wistar rats weighing 250 grams have been used in the analysis (Iwasaki, Motoyuki, et al. 2618). Additionally, experimental groups and surgical procedures were performed on the specimen such as cervical SCI and neurobehavioral assessments that entailed the use of bar grip strength meter and inclined plane test. Furthermore, both BBB open field locomotors score and catwalk gait analysis are employed to assess hind limbs and forelimbs respectively. SAS stat software (JMP) is integrated into the exploration to aid in data analysis (Iwasaki, Motoyuki, et al. 2618).

Application of the Study

The study is applicable to individuals that suffers from Spinal Cord Injury as it is affirmed that cystic cavity is easily prevented by application of QL6 or through injection of both QL6 and NPCs peptides. Significantly, the treatment helps to safeguard endogenous motor neurons in the affected regions, thus, enhance a quicker healing (Iwasaki, Motoyuki, et al. 2625). In the medical field, health experts can readily apply the findings when diagnosing patients with SCI problems, thus, aids in preventing disabilities that arise from the disease.

Conclusion

In essence, the research is of significant value to the health professionals since it provides success to SCI treatment which has had limited achievements. Moreover, application of the Self-assembling peptides (SAP) lowers the post-traumatic apoptosis of the neural cells, hence, facilitating the development of axonal in the thoracic of affected humans. Therefore, the study is of importance to both the hospital physicians and patients suffering from SCI.

Work Cited

Iwasaki, Motoyuki, et al. “Synergistic effects of self-assembling peptide and neural stem/progenitor cells to promote tissue repair and forelimb functional recovery in cervical spinal cord injury.” Biomaterials 35.9 (2014): 2617-2629.

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